Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13936533 | 0.90 | BDKRB1 (0.78) | BDKRB1CYP3A4 | |
| SCHEMBL4521993 | 0.90 | BDKRB1 (0.78) | BDKRB1CYP3A4 | |
| SCHEMBL4958210 | 0.90 | BDKRB1 (0.78) | BDKRB1CYP3A4 | |
| SCHEMBL4958042 | 0.89 | BDKRB1 (0.77) | BDKRB1CYP3A4 | |
| SCHEMBL4957144 | 0.88 | BDKRB1 (0.75) | BDKRB1CYP3A4 | |
| SCHEMBL4957064 | 0.84 | BDKRB1 (0.70) | BDKRB1CYP3A4 | |
| SCHEMBL4958005 | 0.81 | BDKRB1 (0.79) | BDKRB1CYP3A4 | |
| SCHEMBL14272136 | 0.80 | BDKRB1 (0.58) | BDKRB1CYP3A4 | |
| SCHEMBL3531205 | 0.80 | BDKRB1 (0.79) | BDKRB1 | |
| SCHEMBL4959638 | 0.80 | BDKRB1 (0.77) | BDKRB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1878728-A2 | Derivatives of piperazine and higher homologues thereof for the treatment of inflammation-related disorders | Amgen Inc. (US) | 2008-01-16 | — | — | EP | disclosed |