Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7254154 | 0.78 | TAAR1 (0.48) | ESR1ESR2TAAR1SLC6A2MIF | |
| SCHEMBL7259681 | 0.77 | TAAR1 (0.47) | ESR1ESR2TAAR1SLC6A2MIF | |
| SCHEMBL14285183 | 0.75 | ESR1 (0.51) | ESR1ESR2TAAR1SLC6A2MIF | |
| SCHEMBL14285168 | 0.75 | ESR1 (0.51) | ESR1ESR2TAAR1SLC6A2MIF | |
| SCHEMBL14308649 | 0.74 | TRPV1 (0.45) | ESR1ESR2TAAR1SLC6A2SLC7A5 | |
| SCHEMBL9260666 | 0.73 | TAAR1 (0.56) | ESR1ESR2TAAR1SLC6A2SLC7A5 | |
| SCHEMBL10891452 | 0.71 | ESR1 (0.48) | ESR1ESR2TAAR1SLC6A2MIF | |
| SCHEMBL2028390 | 0.70 | SLC7A5 (0.53) | METSLC7A5 | |
| SCHEMBL1840026 | 0.70 | TAAR1 (0.57) | ESR1ESR2TAAR1SLC6A2SLC7A5 | |
| SCHEMBL8813582 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7321056-B2 | Selective peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2008-01-22 | — | — | US | disclosed |