Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 17/20 | 0.87 |
| ▸ | KCNK9 | Q9NPC2 | 13/20 | 0.87 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.87 |
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.79 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.76 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4253897 | 0.90 | KCNK3 (0.93) | KCNK3KCNK9KCNH2MEN1KMT2A | |
| SCHEMBL17013407 | 0.90 | KCNK3 (0.69) | KCNK3KCNK9KCNH2MEN1KMT2A | |
| SCHEMBL16675166 | 0.88 | KCNK3 (0.89) | KCNK3KCNK9KCNH2MEN1KMT2A | |
| SCHEMBL16681527 | 0.87 | KCNK3 (0.87) | KCNK3KCNK9KCNH2MEN1KMT2A | |
| SCHEMBL21377679 | 0.85 | KCNK3 (0.84) | KCNK3KCNK9KCNH2MEN1KMT2A | |
| SCHEMBL1630322 | 0.85 | KMT2A (0.63) | KCNK3KCNK9KCNH2MEN1KMT2A | |
| SCHEMBL23577148 | 0.85 | KCNK3 (0.82) | KCNK3KCNK9MEN1KMT2APOLB | |
| SCHEMBL259666 | 0.85 | KCNK3 (0.87) | KCNK3KCNK9KCNH2MEN1KMT2A | |
| SCHEMBL30608967 | 0.85 | KCNK3 (0.87) | KCNK3KCNK9KCNH2MEN1KMT2A | |
| SCHEMBL19491385 | 0.84 | KCNK3 (0.85) | KCNK3KCNK9KCNH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1878727-A1 | 2-AMINOQUINAZOLINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-16 | — | — | EP | disclosed |