Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10610411 | 0.92 | — | — | |
| Sulfurous Acid SCHEMBL9928922 | 0.91 | — | — | |
| Bicarbonate SCHEMBL226679 | 0.88 | CA4 (0.40) | — | |
| Sulfurous Acid SCHEMBL28661780 | 0.87 | — | — | |
| Bicarbonate SCHEMBL5912779 | 0.87 | CA1 (0.46) | — | |
| Sulfurous Acid SCHEMBL1533868 | 0.87 | CA1 (0.50) | — | |
| Sulfurous Acid SCHEMBL889 | 0.87 | — | — | |
| Sulfurous Acid SCHEMBL29410199 | 0.87 | CA1 (0.50) | — | |
| Sulfurous Acid SCHEMBL4886336 | 0.87 | — | — | |
| Acetic Acid SCHEMBL8164708 | 0.85 | FFAR3 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111804441-B | Method for regulating and controlling flotation of high-sulfur iron-containing sulfide ore by adding oxygen producing agent in ore grinding process | 中南大学 | 2022-03-01 | — | — | CN | claimed |
| CN-111804441-A | Method for regulating and controlling flotation of high-sulfur iron-containing sulfide ore by adding oxygen producing agent in ore grinding process | 中南大学 | 2020-10-23 | — | — | CN | claimed |
| CN-109540825-A | A method of for analyzing ferro-phosphorus form content in sludge | 同济大学 | 2019-03-29 | — | — | CN | claimed |
| CN-111804441-B | Method for regulating and controlling flotation of high-sulfur iron-containing sulfide ore by adding oxygen producing agent in ore grinding process | 中南大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-111804441-A | Method for regulating and controlling flotation of high-sulfur iron-containing sulfide ore by adding oxygen producing agent in ore grinding process | 中南大学 | 2020-10-23 | — | — | CN | disclosed |
| CN-109540825-A | A method of for analyzing ferro-phosphorus form content in sludge | 同济大学 | 2019-03-29 | — | — | CN | disclosed |
| CN-102089290-B | Triazole derivatives useful for the treatment of diseases | PFIZER | 2013-09-04 | — | — | CN | disclosed |
| EP-2300443-B1 | TRIAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DISEASES | PFIZER LTD (GB) | 2012-12-12 | — | — | EP | disclosed |
| US-8263623-B2 | Triazol derivatives useful for the treatment of diseases | PFIZER INC. (US) | 2012-09-11 | — | — | US | disclosed |
| CN-102089290-A | Triazole derivatives useful for the treatment of diseases | PFIZER LTD | 2011-06-08 | — | — | CN | disclosed |
| EP-2300443-A1 | TRIAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DISEASES | Pfizer Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| EP-1597235-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-11-23 | — | — | EP | disclosed |
| US-20040192666-A1 | Nonnucleoside reverse transcriptase inhibitors | ROCHE PALO ALTO LLC | 2004-09-30 | — | — | US | disclosed |
| WO-2004074257-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-02 | — | — | WO | disclosed |
| EP-0839798-A2 | Intermediates for preparating non-peptide retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5670675-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1997-09-23 | — | — | US | disclosed |
| US-5545750-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS | ABBOTT LABORATORIES (US) | 1996-08-13 | — | — | US | disclosed |
| US-5142056-A | Human immunodeficiency virus protease inhibitor | ABBOTT LABORATORIES (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0402646-A1 | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0080272-A2 | Shrink-resist treatment of wool | SOUTH AFRICAN INVENTIONS DEVELOPMENT CORPORATION (ZA) | 1983-06-01 | — | — | EP | disclosed |