Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.55 |
| ▸ | PIM1 | P11309 | 13/20 | 0.47 |
| ▸ | GALR2 | O43603 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 9/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4340286 | 0.92 | FYN (0.66) | FYNPIM1PIM2FLT3KCNH2 | |
| SCHEMBL14308670 | 0.87 | FYN (0.68) | FYNPIM1GALR2RETPIK3CG | |
| SCHEMBL4342860 | 0.84 | FYN (0.58) | FYNPIM1PIM2FLT3KCNH2 | |
| SCHEMBL14308654 | 0.84 | FYN (0.55) | FYNPIM1RETPIK3CG | |
| SCHEMBL4330143 | 0.84 | FYN (0.57) | FYNPIM1PIM2FLT3KCNH2 | |
| SCHEMBL4330269 | 0.82 | FYN (0.56) | FYNPIM1PIM2FLT3KCNH2 | |
| SCHEMBL4558598 | 0.82 | FYN (0.78) | FYNPIM1PIM2FLT3KCNH2 | |
| SCHEMBL4338231 | 0.81 | PIM1 (0.67) | FYNPIM1PIM2FLT3KCNH2 | |
| SCHEMBL14357041 | 0.81 | FYN (0.72) | FYNPIM1GALR2RETPIK3CG | |
| SCHEMBL14302628 | 0.79 | FYN (0.57) | FYNPIM1RETPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1873157-A1 | Pyrazolopyrimidines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-01-02 | — | — | EP | disclosed |