SCHEMBL1431069

SCHEMBL1431069

O=C(OC(C(=O)O)C(O)C(=O)O)C(O)C(O)C(=O)OC(C(=O)O)C(O)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
SRC P12931 1/20 0.38
TP53 P04637 2/20 0.32
PGD P52209 2/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP9 P14780 1/20 0.31
MMP13 P45452 1/20 0.31
HTT P42858 1/20 0.31
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
CYP2C9 P11712 1/20 0.31
PDE4A P27815 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5691242 0.97 TSHR (0.50) TSHRSRCTP53PGDMMP1
SCHEMBL20565537 0.97 TSHR (0.43) TSHRSRCTP53PGDMMP1
SCHEMBL8145944 0.97 TSHR (0.50) TSHRSRCTP53PGDMMP1
SCHEMBL7707382 0.97 TSHR (0.43) TSHRSRCTP53PGDMMP1
SCHEMBL5691239 0.97 TSHR (0.50) TSHRSRCTP53PGDMMP1
SCHEMBL184960 0.97 TSHR (0.50) TSHRSRCTP53PGDMMP1
SCHEMBL2200092 0.97 TSHR (0.50) TSHRSRCTP53PGDMMP1
SCHEMBL11054851 0.95 TSHR (0.48) TSHRSRCTP53
SCHEMBL20565536 0.95 TSHR (0.48) TSHRSRCTP53
SCHEMBL29292859 0.95 TSHR (0.48) TSHRSRCTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108463176-A Temporary occlusion balloon device and method for preventing blood flow through a vascular puncture 斯佩克特尼克斯公司 2018-08-28 CN disclosed
CN-107519136-A A kind of Choline Chloride Succinate lyophilized formulations and preparation method thereof 西安力邦医药科技有限责任公司 2017-12-29 CN disclosed
EP-3157986-A1 CURABLE POLYMERS COMPRISING SILSESQUIOXANE POLYMER CORE AND SILSESQUIOXANE POLYMER OUTER LAYER AND METHODS 3M Innovative Properties Company (US) 2017-04-26 EP disclosed
EP-3080219-A1 CURABLE SILSESQUIOXANE POLYMERS, COMPOSITIONS, ARTICLES, AND METHODS 3M Innovative Properties Company (US) 2016-10-19 EP disclosed
WO-2015195268-A1 CURABLE POLYMERS COMPRISING SILSESQUIOXANE POLYMER CORE AND SILSESQUIOXANE POLYMER OUTER LAYER AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-12-23 WO disclosed
WO-2015088932-A1 CURABLE SILSESQUIOXANE POLYMERS, COMPOSITIONS, ARTICLES, AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-06-18 WO disclosed
EP-2300202-A1 METHOD OF REDUCING EMISSIONS FROM WOOD AND WOOD-BASED MATERIALS Bundesanstalt Für Materialforschung Und -Prüfung (BAM) (DE) 2011-03-30 EP disclosed
WO-2009156231-A1 METHOD OF REDUCING EMISSIONS FROM WOOD AND WOOD-BASED MATERIALS BAM Bundesanstalt für Materialforschung und -prüfung (DE) 2009-12-30 WO disclosed