Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 19/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14050671 | 0.89 | IGF1R (0.56) | IGF1R | |
| SCHEMBL12439798 | 0.73 | IGF1R (0.65) | IGF1R | |
| SCHEMBL14050570 | 0.72 | IGF1R (0.61) | IGF1R | |
| SCHEMBL4012617 | 0.71 | IGF1R (1.00) | IGF1R | |
| SCHEMBL14050425 | 0.70 | IGF1R (0.56) | IGF1R | |
| SCHEMBL12438468 | 0.70 | IGF1R (0.67) | IGF1R | |
| SCHEMBL14162125 | 0.69 | IGF1R (0.64) | IGF1R | |
| SCHEMBL12438567 | 0.69 | IGF1R (0.68) | IGF1R | |
| SCHEMBL12438231 | 0.69 | IGF1R (0.42) | IGF1R | |
| SCHEMBL12439843 | 0.68 | IGF1R (0.64) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008005538-A2 | METHODS OF USING IGF1R AND ABL KINASE MODULATORS | EXELIXIS, INC. (US) | 2008-01-10 | — | — | WO | disclosed |