Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 19/20 | 0.73 |
| ▸ | EGLN3 | Q9H6Z9 | 17/20 | 0.73 |
| ▸ | EGLN2 | Q96KS0 | 16/20 | 0.73 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14312550 | 0.91 | EGLN1 (0.80) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL13017086 | 0.88 | EGLN1 (0.76) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL17633210 | 0.87 | EGLN1 (0.83) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL17633147 | 0.85 | EGLN1 (0.81) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL14312356 | 0.85 | EGLN1 (0.75) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL17633104 | 0.85 | EGLN1 (1.00) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL3777720 | 0.83 | EGLN1 (0.83) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL17633391 | 0.82 | EGLN1 (1.00) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL14312562 | 0.81 | EGLN1 (0.71) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL17633114 | 0.81 | EGLN1 (0.86) | EGLN1EGLN3EGLN2CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257170-B1 | TETRAHYDROFUROPYRIDONES | MERCK SHARP & DOHME (US) | 2012-12-26 | — | — | EP | claimed |
| EP-2257170-B1 | TETRAHYDROFUROPYRIDONES | MERCK SHARP & DOHME (US) | 2012-12-26 | — | — | EP | disclosed |