Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1625383 | 0.90 | KCNQ3 (0.54) | BACE1MEN1HTTKMT2AMAPT | |
| SCHEMBL1624457 | 0.89 | BACE1 (0.48) | BACE1MEN1HTTKMT2AKDM4E | |
| SCHEMBL1622986 | 0.88 | MEN1 (0.49) | BACE1MEN1HTTKMT2A | |
| SCHEMBL1624898 | 0.88 | BACE1 (0.47) | BACE1MEN1HTTKMT2AKDM4E | |
| SCHEMBL27756790 | 0.86 | BACE1 (0.46) | BACE1MEN1HTTKMT2AKDM4E | |
| SCHEMBL1623023 | 0.86 | MEN1 (0.49) | BACE1MEN1HTTKMT2AKDM4E | |
| SCHEMBL1624920 | 0.86 | BACE1 (0.45) | BACE1MEN1HTTKMT2A | |
| SCHEMBL1624738 | 0.86 | MAPT (0.47) | BACE1MEN1HTTKMT2AKDM4E | |
| SCHEMBL1625441 | 0.86 | BACE1 (0.45) | BACE1MEN1HTTKMT2A | |
| SCHEMBL1624835 | 0.85 | MEN1 (0.65) | BACE1MEN1HTTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008014291-A2 | COMPOUNDS AND COMPOSITIONS AS HEDGEHOG SIGNALING PATHWAY MODULATORS | IRM LLC (BM) | 2008-01-31 | — | — | WO | disclosed |