SCHEMBL1432178

SCHEMBL1432178

CCC(C)[C@@H](NC)C(=O)N[C@H](Cc1ccc(Cl)c(Cl)c1)C(=O)NCc1ccc(N)nc1C

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F2 P00734 16/20 0.51
MASP2 O00187 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1434219 0.85 KLKB1 (0.42) MASP2
SCHEMBL1431802 0.84 F2 (0.50) F2MASP2
SCHEMBL3141523 0.84 F2 (0.50) F2MASP2
SCHEMBL1432494 0.82 F2 (0.51) F2MASP2
SCHEMBL3147419 0.82 F2 (0.51) F2MASP2
SCHEMBL1432357 0.82 F2 (0.53) F2MASP2
SCHEMBL3148675 0.82 F2 (0.53) F2MASP2
SCHEMBL1432535 0.81 F2 (0.50) F2MASP2
SCHEMBL1432531 0.81 F2 (0.50) F2MASP2
Trifluoroacetic Acid SCHEMBL1432772 0.80 PSMB5 (0.43) MASP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2300428-A1 AMINOPYRIDINE DERIVATIVES Vantia Limited (GB) 2011-03-30 EP disclosed