SCHEMBL14322129

SCHEMBL14322129

c1ccn(C(c2ccc(C(n3cccc3)n3cccc3)cc2)n2cccc2)c1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.35
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
GRM5 P41594 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14397071 0.66 CYP19A1 (0.59) TDP1MAPTNPSR1
SCHEMBL940326 0.66 TDP1 (0.50) HSD17B10POLBSMN1; SMN2TDP1MAPT
SCHEMBL4880953 0.65 CYP19A1 (0.56) TDP1MAPTNPSR1
SCHEMBL7009772 0.61 CYP2D6 (0.54) HSD17B10MAPTNPSR1
SCHEMBL5640922 0.56
SCHEMBL5639791 0.56
SCHEMBL30521601 0.54
Hydrogen Sulfide SCHEMBL28494796 0.54
SCHEMBL2329633 0.52
SCHEMBL3153367 0.52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2551271-B1 COPOLYMER CONTAINING FLUORENYLPORPHYRIN-BENZENE, PREPARATION METHOD AND USE THEREOF OCEANS KING LIGHTING SCIENCE (CN) 2014-08-27 EP claimed
US-8546512-B2 Copolymer containing fluorenylporphyrin-benzene, preparation method and use thereof OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2013-10-01 US claimed
EP-2551271-A1 COPOLYMER CONTAINING FLUORENYLPORPHYRIN-BENZENE, PREPARATION METHOD AND USE THEREOF Ocean's King Lighting Science&Technology Co., Ltd. (CN) 2013-01-30 EP claimed
US-20120329979-A1 COPOLYMER CONTAINING FLUORENYLPORPHYRIN-BENZENE, PREPARATION METHOD AND USE THEREOF OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2012-12-27 US claimed
EP-2551271-B1 COPOLYMER CONTAINING FLUORENYLPORPHYRIN-BENZENE, PREPARATION METHOD AND USE THEREOF OCEANS KING LIGHTING SCIENCE (CN) 2014-08-27 EP disclosed
US-8546512-B2 Copolymer containing fluorenylporphyrin-benzene, preparation method and use thereof OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2013-10-01 US disclosed
EP-2551271-A1 COPOLYMER CONTAINING FLUORENYLPORPHYRIN-BENZENE, PREPARATION METHOD AND USE THEREOF Ocean's King Lighting Science&Technology Co., Ltd. (CN) 2013-01-30 EP disclosed
US-20120329979-A1 COPOLYMER CONTAINING FLUORENYLPORPHYRIN-BENZENE, PREPARATION METHOD AND USE THEREOF OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2012-12-27 US disclosed