Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5907158 | 1.00 | TSHR (0.40) | TSHRTDP1LMNA | |
| SCHEMBL1614446 | 0.85 | TSHR (0.41) | TSHRTDP1LMNA | |
| SCHEMBL27511160 | 0.83 | — | — | |
| SCHEMBL17581954 | 0.82 | TSHR (0.44) | TSHRTDP1 | |
| SCHEMBL7910340 | 0.82 | TSHR (0.44) | TSHRTDP1 | |
| SCHEMBL18124714 | 0.80 | TSHR (0.37) | TSHRTDP1LMNA | |
| SCHEMBL14284903 | 0.80 | TSHR (0.37) | TSHRTDP1LMNA | |
| SCHEMBL10290190 | 0.80 | TSHR (0.37) | TSHRTDP1LMNA | |
| SCHEMBL1614423 | 0.80 | TSHR (0.37) | TSHRTDP1LMNA | |
| SCHEMBL344706 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174384-A1 | THERMALLY DECOMPOSABLE POLYMER COMPOSITIONS INCORPORATING THERMALLY ACTIVATED BASE GENERATORS | PROMERUS LLC (US) | 2012-12-20 | — | — | WO | disclosed |