⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2048690 | 0.65 | — | — | |
| SCHEMBL2043243 | 0.65 | — | — | |
| SCHEMBL2043269 | 0.60 | — | — | |
| SCHEMBL8821221 | 0.60 | — | — | |
| SCHEMBL3149420 | 0.56 | — | — | |
| SCHEMBL5514045 | 0.52 | — | — | |
| SCHEMBL2841282 | 0.48 | — | — | |
| SCHEMBL13369627 | 0.48 | — | — | |
| SCHEMBL36405 | 0.48 | — | — | |
| SCHEMBL18892488 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098300-A1 | Compounds Comprising A Cyclobutoxy Group | UCB PHARMA, S.A. (BE) | 2011-04-28 | — | — | US | disclosed |
| EP-2300426-A1 | COMPOUNDS COMPRISING A CYCLOBUTOXY GROUP | UCB Pharma, S.A. (BE) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009147149-A1 | COMPOUNDS COMPRISING A CYCLOBUTOXY GROUP | UCB PHARMA, S.A. (BE) | 2009-12-10 | — | — | WO | disclosed |