Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | GLA | P06280 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | CA12 | O43570 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CA3 | P07451 | 2/20 | 0.65 |
| ▸ | CA4 | P22748 | 2/20 | 0.65 |
| ▸ | CA6 | P23280 | 2/20 | 0.65 |
| ▸ | CA7 | P43166 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 2/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.65 |
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | MIF | P14174 | 1/20 | 0.51 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989019 | 0.88 | MAOB (0.54) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL12045958 | 0.85 | KDM4E (0.57) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL6109694 | 0.84 | MIF (0.64) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL1406253 | 0.83 | SLC16A3 (0.59) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL14326438 | 0.82 | CA12 (0.62) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL13432123 | 0.80 | MAOB (0.67) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL1406462 | 0.79 | MAOB (1.00) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL2031783 | 0.76 | MAOB (1.00) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL16267284 | 0.76 | MIF (0.64) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL16418951 | 0.75 | MAOB (0.51) | MAOBKDM4EGLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338401-B2 | Coumarin-amide derivatives and its preparation, said drug composition and its use | INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2012-12-25 | — | — | US | disclosed |