Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 16/20 | 0.71 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12781024 | 0.90 | AOC3 (0.77) | AOC3GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL16606221 | 0.87 | AOC3 (0.78) | AOC3GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL2068499 | 0.85 | AOC3 (0.80) | AOC3GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL1432878 | 0.84 | AOC3 (0.74) | AOC3GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL1432804 | 0.83 | AOC3 (0.76) | AOC3GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL1432620 | 0.83 | AOC3 (0.73) | AOC3GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL1432309 | 0.83 | AOC3 (1.00) | AOC3 | |
| SCHEMBL27829408 | 0.82 | AOC3 (0.64) | AOC3GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL1432665 | 0.82 | AOC3 (0.68) | AOC3SYKGAAMAPTKDM4E | |
| SCHEMBL27809188 | 0.81 | AOC3 (0.82) | AOC3GAAMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300430-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-Tech Ueno, Ltd. (JP) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009145360-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-12-03 | — | — | WO | disclosed |