Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 12/20 | 0.47 |
| ▸ | BCL2 | P10415 | 12/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2388665 | 0.96 | BCL2 (0.50) | BCL2L1BCL2 | |
| SCHEMBL1957426 | 0.86 | BCL2 (0.60) | BCL2 | |
| SCHEMBL2862158 | 0.86 | BCL2 (0.60) | BCL2 | |
| SCHEMBL2862147 | 0.86 | BCL2 (0.60) | BCL2 | |
| SCHEMBL2387374 | 0.84 | BCL2 (0.59) | BCL2 | |
| SCHEMBL19424669 | 0.82 | BCL2 (0.55) | BCL2 | |
| SCHEMBL19424670 | 0.82 | BCL2 (0.55) | BCL2 | |
| SCHEMBL2388106 | 0.80 | BCL2L1 (0.52) | BCL2L1BCL2 | |
| SCHEMBL2390310 | 0.78 | BCL2 (0.46) | BCL2L1BCL2 | |
| SCHEMBL2389447 | 0.77 | BCL2L1 (0.53) | BCL2L1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8343967-B2 | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBOTT LABORATORIES (US) | 2013-01-01 | — | — | US | claimed |