SCHEMBL143317

SCHEMBL143317

[CH2]C=C(C)[CH]C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15062708 1.00
SCHEMBL834273 0.77
SCHEMBL21131544 0.77
SCHEMBL834274 0.77
SCHEMBL3462937 0.72
SCHEMBL3462936 0.72
SCHEMBL22212 0.70
SCHEMBL16178515 0.70
SCHEMBL22211 0.70
SCHEMBL8915241 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022040604-A1 USE OF DP1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF VIRAL RESPIRATORY TRACT INFECTIONS AND DYSREGULATED IMMUNE RESPONSE IN AGED AND AGING PATIENTS BioAge Labs, Inc. (US) 2022-02-24 WO disclosed
US-10261090-B2 Glutathione-detecting fluorescent probe THE UNIVERSITY OF TOKYO (JP) 2019-04-16 US disclosed
US-20170355642-A1 MONO- AND BISALKYLENETRIALKOXYSILANE DISPERSANTS FOR HYDRAULIC BINDERS BASF SE (DE) 2017-12-14 US disclosed
US-20170145005-A1 KINASE INHIBITOR THE UNIVERSITY OF TOKYO (JP) 2017-05-25 US disclosed
US-20170045525-A1 GLUTATHIONE-DETECTING FLUORESCENT PROBE THE UNIVERSITY OF TOKYO (JP) 2017-02-16 US disclosed
US-20160368895-A1 PULMONARY HYPERTENSION TREATING AGENT THE UNIVERSITY OF TOKYO (JP) 2016-12-22 US disclosed
US-9440938-B2 Sulfonamide derivative having PGD2 receptor antagonistic activity SHIONOGI & CO., LTD. (JP) 2016-09-13 US disclosed
EP-2797946-B1 SIALIC ACID DIMERS BROSSMER REINHARD (DE) 2016-05-04 EP disclosed
US-9260467-B2 Sialic acid dimers BROSSMER REINHARD (DE) 2016-02-16 US disclosed
US-20150158833-A1 SULFONAMIDE DERIVATIVE HAVING PGD2 RECEPTOR ANTAGONISTIC ACTIVITY SHIONOGI & CO (JP) 2015-06-11 US disclosed
US-8153793-B2 Sulfonamide derivative having PGD2 receptor antagonistic activity SHIONOGI & CO., LTD. (JP) 2012-04-10 US disclosed
US-20120059061-A1 NOVEL ANTI-INFLAMMATORY COMPOUNDS THE UNIVERSITY OF TOKYO (JP) 2012-03-08 US disclosed
EP-2407459-A1 Synthetic intermediate in the production of a sulfonamide derivative having PGD2 receptor antagonistic activity Shionogi & Co., Ltd. (JP) 2012-01-18 EP disclosed
EP-2407453-A1 PGD2 receptor antagonist Shionogi & Co., Ltd. (JP) 2012-01-18 EP disclosed
US-20110105457-A1 HETEROCYCLIC COMPOUND HAVING INHIBITORY ACTIVITY ON PI3K SHIONOGI & CO., LTD. 2011-05-05 US disclosed
EP-1939175-A1 SULFONAMIDE DERIVATIVE HAVING PGD2 RECEPTOR ANTAGONISTIC ACTIVITY Shionogi&Co., Ltd. (JP) 2008-07-02 EP disclosed
EP-0513580-B1 Alpha-phenyl-acrylic acid derivatives, process for their preparation and their use as parasiticides and fungicides BASF AG (DE) 1996-10-23 EP disclosed
US-5416068-A Alpha-phenylacrylic acid derivatives, their preparation and their use for controlling pests and harmful fungi BASF AKTIENGESELLSCHAFT (DE) 1995-05-16 US disclosed
US-5298527-A Insecticides BASF AKTIENGESELLSCHAFT (DE) 1994-03-29 US disclosed
EP-0513580-A2 Alpha-phenyl-acrylic acid derivatives, process for their preparation and their use as parasiticides and fungicides BASF Aktiengesellschaft (DE) 1992-11-19 EP disclosed