Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29653646 | 1.00 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL22532 | 0.96 | — | — | |
| SCHEMBL11341378 | 0.96 | TSHR (0.46) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL28663513 | 0.96 | TSHR (0.46) | TSHRLMNATHRBALDH1A1TDP1 | |
| Bromide SCHEMBL2253287 | 0.92 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Hydrogen Sulfide SCHEMBL4743461 | 0.92 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Water SCHEMBL16164192 | 0.92 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Water SCHEMBL2474010 | 0.92 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL9798977 | 0.92 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Ammonia Solution, Strong SCHEMBL21753667 | 0.92 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222751-B1 | CURABLE COMPOSITIONS CONSISTING OF SILANES WITH THREE HYDROLYSABLE GROUPS | HENKEL AG & CO KGAA (DE) | 2011-07-06 | — | — | EP | disclosed |
| EP-2176315-B1 | CURABLE COMPOSITIONS COMPOSED OF SILANES WITH TWO HYDROLYZABLE GROUPS | HENKEL AG & CO KGAA (DE) | 2011-03-30 | — | — | EP | disclosed |
| EP-2222751-A2 | CURABLE COMPOSITIONS CONSISTING OF SILANES WITH THREE HYDROLYSABLE GROUPS | Henkel AG & Co. KGaA (DE) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009065950-A2 | CURABLE COMPOSITIONS CONSISTING OF SILANES WITH THREE HYDROLYSABLE GROUPS | HENKEL AG & CO. KGAA (DE) | 2009-05-28 | — | — | WO | disclosed |
| EP-1678254-B1 | POLYMERS WITH IMPROVED STRENGTH COMPRISING MIXED OXYALKYL UNITS | HENKEL KGAA (DE) | 2007-05-09 | — | — | EP | disclosed |
| EP-1685175-A1 | POLYURETHANE COMPOSITIONS WITH NCO AND SILYL REACTIVITY | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-08-02 | — | — | EP | disclosed |
| EP-1678254-A1 | POLYMERS WITH IMPROVED STRENGTH COMPRISING MIXED OXYALKYL UNITS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005049684-A1 | POLYURETHANE COMPOSITIONS WITH NCO AND SILYL REACTIVITY | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-06-02 | — | — | WO | disclosed |
| WO-2005047394-A1 | POLYMERS WITH IMPROVED STRENGTH COMPRISING MIXED OXYALKYL UNITS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-05-26 | — | — | WO | disclosed |
| WO-2005042610-A2 | STORAGE-STABLE POLYURETHANE COMPRISING SILYL GROUPS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-05-12 | — | — | WO | disclosed |
| EP-1074569-A1 | Polyol mixtures for polyurethanes with improved hydrolytic stability | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-07 | — | — | EP | disclosed |