Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4638871 | 0.90 | PARP1 (0.38) | PARP1NNMTSYKPDPK1GDA | |
| SCHEMBL14337344 | 0.90 | PARP1 (0.38) | PARP1NNMTSYKPDPK1GDA | |
| SCHEMBL4638632 | 0.80 | IP6K1 (0.36) | PDPK1 | |
| SCHEMBL14035177 | 0.77 | PARP1 (0.43) | PARP1NNMTPDPK1GDA | |
| SCHEMBL5521728 | 0.76 | RXFP1 (0.34) | PDPK1 | |
| SCHEMBL14035182 | 0.72 | MEN1 (0.42) | PARP1 | |
| SCHEMBL4638949 | 0.70 | IP6K1 (0.34) | PDPK1 | |
| SCHEMBL4639102 | 0.69 | PARP1 (0.43) | PARP1NNMTPDPK1GDA | |
| SCHEMBL14347857 | 0.68 | PARP1 (0.49) | PARP1NNMTPDPK1GDA | |
| SCHEMBL14348180 | 0.65 | PARP1 (0.53) | PARP1NNMTPDPK1GDA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304084-B2 | 6-[(4,5-Dihydro-1H-imidazol-2-yl)amino]-7-methyl-1H-benzimidazole-4-carbonitrile and its preferred salt | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2007-12-04 | — | — | US | disclosed |