Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PRF1 | P14222 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14337140 | 0.89 | BACE1 (0.41) | BACE1IKBKBCHUKNPC1ACLY | |
| SCHEMBL14337031 | 0.85 | BACE1 (0.45) | BACE1NPC1AHRKEAP1MEN1 | |
| SCHEMBL14337311 | 0.84 | BACE1 (0.38) | BACE1IKBKBCHUKNPC1ACLY | |
| SCHEMBL14337255 | 0.83 | BACE1 (0.41) | BACE1NPC1AHRKEAP1MEN1 | |
| SCHEMBL14337176 | 0.80 | BACE1 (0.41) | BACE1NPC1AHRKEAP1MEN1 | |
| SCHEMBL14337259 | 0.80 | AHR (0.45) | BACE1IKBKBCHUKAHRKEAP1 | |
| SCHEMBL14337504 | 0.79 | BACE1 (0.40) | BACE1IKBKBCHUKACLYAHR | |
| SCHEMBL14337254 | 0.79 | BACE1 (0.40) | BACE1NPC1AHRKEAP1MEN1 | |
| SCHEMBL14337508 | 0.77 | SIRT2 (0.48) | BACE1AHRKEAP1ALDH1A1MAPT | |
| SCHEMBL14337445 | 0.75 | AHR (0.46) | BACE1AHRKEAP1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312284-B2 | Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby | MITSUI CHEMICALS, INC. (JP) | 2007-12-25 | — | — | US | disclosed |
| US-7312284-B2 | Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby | MITSUI CHEMICALS, INC. (JP) | 2007-12-25 | — | — | US | disclosed |