Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 9/20 | 0.69 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14336844 | 1.00 | NPY5R (0.69) | NPY5RSLC18A3SIGMAR1CCR5LIPG | |
| SCHEMBL14336836 | 0.82 | NPY5R (0.70) | NPY5R | |
| SCHEMBL14336767 | 0.81 | NPY5R (1.00) | NPY5RCCR5 | |
| SCHEMBL14336715 | 0.81 | NPY5R (1.00) | NPY5RCCR5 | |
| SCHEMBL14336641 | 0.80 | NPY5R (1.00) | NPY5R | |
| SCHEMBL14336713 | 0.80 | NPY5R (0.79) | NPY5RCCR5 | |
| SCHEMBL14336630 | 0.80 | NPY5R (1.00) | NPY5R | |
| SCHEMBL14336762 | 0.80 | NPY5R (0.79) | NPY5RCCR5 | |
| SCHEMBL14336845 | 0.79 | NPY5R (0.78) | NPY5RCCR5 | |
| SCHEMBL14336638 | 0.79 | NPY5R (0.78) | NPY5RCCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304076-B2 | Neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-04 | — | — | US | disclosed |
| US-7304076-B2 | Neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-04 | — | — | US | disclosed |