Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.30 |
| ▸ | CNR2 | P34972 | 3/20 | 0.30 |
| ▸ | FASN | P49327 | 1/20 | 0.30 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17070236 | 0.96 | ESR2 (0.32) | ESR2L3MBTL1IDH1MMP12DHODH | |
| SCHEMBL16978443 | 0.90 | S1PR1 (0.36) | L3MBTL1DHODHP2RY14 | |
| SCHEMBL10027435 | 0.90 | ESR2 (0.36) | ESR2FASN | |
| SCHEMBL10014187 | 0.89 | ESR2 (0.41) | ESR2L3MBTL1IDH1MMP12DHODH | |
| SCHEMBL18733825 | 0.89 | ESR2 (0.35) | ESR2FASN | |
| SCHEMBL12895681 | 0.88 | FASN (0.36) | FASN | |
| SCHEMBL17070242 | 0.87 | ESR2 (0.34) | ESR2FASN | |
| SCHEMBL10018753 | 0.87 | — | — | |
| SCHEMBL17070204 | 0.86 | ESR2 (0.33) | ESR2FASN | |
| SCHEMBL11957367 | 0.85 | GRM2 (0.31) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7303791-B2 | Liquid crystals having a terminal polar radical and a terminal CH3 group and simultaneously having very high specific resistances and low threshold voltages requiring a high clearing point and low rotational viscosity; matrices | MERCK PATENT GMBH (DE) | 2007-12-04 | — | — | US | disclosed |
| US-7303791-B2 | Liquid crystals having a terminal polar radical and a terminal CH3 group and simultaneously having very high specific resistances and low threshold voltages requiring a high clearing point and low rotational viscosity; matrices | MERCK PATENT GMBH (DE) | 2007-12-04 | — | — | US | disclosed |