Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14307883 | 0.92 | TRPV1 (0.66) | TRPV1 | |
| SCHEMBL4975272 | 0.92 | TRPV1 (0.66) | TRPV1 | |
| SCHEMBL4975461 | 0.83 | TRPV1 (0.72) | TRPV1 | |
| SCHEMBL4974085 | 0.83 | TRPV1 (0.70) | TRPV1 | |
| SCHEMBL14318782 | 0.83 | TRPV1 (0.72) | TRPV1 | |
| SCHEMBL4975516 | 0.83 | TRPV1 (0.75) | TRPV1 | |
| SCHEMBL4976247 | 0.83 | TRPV1 (0.75) | TRPV1 | |
| SCHEMBL4973528 | 0.82 | TRPV1 (0.69) | TRPV1 | |
| SCHEMBL4976351 | 0.81 | TRPV1 (0.67) | TRPV1 | |
| SCHEMBL27619086 | 0.81 | TRPV1 (0.69) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304059-B2 | Substituted quinazolin-4-ylamine analogues | NEUROGEN CORPORATION (US) | 2007-12-04 | — | — | US | disclosed |