Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708477 | 0.81 | KMT2A (0.62) | NPC1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL24086168 | 0.80 | MAPT (0.62) | NPC1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL8011213 | 0.80 | MAPT (0.60) | NPC1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1262943 | 0.79 | MAPT (0.68) | NPC1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL14607771 | 0.79 | MAPT (0.68) | NPC1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1262942 | 0.79 | MAPT (0.68) | NPC1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL15543287 | 0.77 | MAPT (0.70) | NPC1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL14104341 | 0.74 | KMT2A (0.61) | NPC1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL8011206 | 0.73 | MAPT (0.60) | NPC1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL8011209 | 0.73 | MAPT (0.60) | NPC1MAPTRAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7311736-B2 | Use of tetra-azapentamethine compounds as direct dyeing agents and novel tetra-azapentamethine compounds | L'OREAL (FR) | 2007-12-25 | — | — | US | disclosed |
| US-7311736-B2 | Use of tetra-azapentamethine compounds as direct dyeing agents and novel tetra-azapentamethine compounds | L'OREAL (FR) | 2007-12-25 | — | — | US | disclosed |