Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.87 |
| ▸ | CCR5 | P51681 | 12/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5148952 | 0.93 | KCNH2 (1.00) | KCNH2CCR5 | |
| SCHEMBL5148957 | 0.93 | KCNH2 (1.00) | KCNH2CCR5 | |
| SCHEMBL13178981 | 0.88 | KCNH2 (0.90) | KCNH2CCR5 | |
| SCHEMBL3079829 | 0.87 | KCNH2 (1.00) | KCNH2CCR5 | |
| SCHEMBL3079826 | 0.87 | KCNH2 (1.00) | KCNH2CCR5 | |
| SCHEMBL3070606 | 0.85 | KCNH2 (1.00) | KCNH2CCR5 | |
| SCHEMBL3070604 | 0.85 | KCNH2 (1.00) | KCNH2CCR5 | |
| SCHEMBL2575130 | 0.84 | KCNH2 (0.90) | KCNH2CCR5 | |
| SCHEMBL2575126 | 0.84 | KCNH2 (0.90) | KCNH2CCR5 | |
| SCHEMBL3068338 | 0.84 | KCNH2 (0.86) | KCNH2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309790-B2 | Chemical compounds | PFIZER INC (US) | 2007-12-18 | — | — | US | disclosed |