Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.43 |
| ▸ | FEN1 | P39748 | 2/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.38 |
| ▸ | KAT7 | O95251 | 1/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028507 | 0.92 | SMARCA2 (0.49) | ALOX5APFEN1SMARCA2SMARCA4PBRM1 | |
| SCHEMBL14339609 | 0.88 | SMARCA2 (0.45) | ALOX5APFEN1SMARCA2SMARCA4PBRM1 | |
| SCHEMBL4942358 | 0.84 | SMARCA2 (0.51) | ALOX5APFEN1SMARCA2SMARCA4PBRM1 | |
| SCHEMBL4947268 | 0.84 | SMARCA2 (0.51) | ALOX5APFEN1SMARCA2SMARCA4PBRM1 | |
| SCHEMBL7015204 | 0.82 | SMARCA2 (0.49) | ALOX5APFEN1SMARCA2SMARCA4PBRM1 | |
| SCHEMBL14028510 | 0.81 | SMARCA2 (0.53) | ALOX5APFEN1SMARCA2SMARCA4PBRM1 | |
| SCHEMBL4944352 | 0.81 | IKBKB (0.52) | SMARCA2SMARCA4PBRM1IKBKBPROKR1 | |
| SCHEMBL4939836 | 0.80 | PRMT5 (0.47) | ALOX5APFEN1SMARCA2SMARCA4PBRM1 | |
| SCHEMBL14046508 | 0.80 | SMARCA2 (0.54) | ALOX5APFEN1SMARCA2SMARCA4PBRM1 | |
| SCHEMBL14339652 | 0.79 | PRMT5 (0.41) | ALOX5APFEN1SMARCA2SMARCA4PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326856-B1 | PYRIDINE DERIVATIVES WITH IKB-KINASE (IKK-BETA) INHIBITING ACTIVITY | BAYER HEALTHCARE AG (DE) | 2007-12-19 | — | — | EP | disclosed |