Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4947378 | 0.91 | IKBKB (0.49) | IKBKB | |
| SCHEMBL4939836 | 0.81 | PRMT5 (0.47) | — | |
| SCHEMBL4945873 | 0.81 | IKBKB (0.49) | IKBKB | |
| SCHEMBL4947301 | 0.80 | IKBKB (0.65) | IKBKBCHUK | |
| SCHEMBL14339735 | 0.79 | PRMT5 (0.40) | IKBKB | |
| SCHEMBL4601001 | 0.78 | IKBKB (0.77) | IKBKBCHUK | |
| SCHEMBL14339767 | 0.78 | IKBKB (0.44) | IKBKBCHUK | |
| SCHEMBL5424220 | 0.77 | PRMT5 (0.51) | IKBKB | |
| SCHEMBL4509466 | 0.77 | ALOX5AP (0.42) | IKBKB | |
| SCHEMBL4946404 | 0.76 | PRMT5 (0.47) | IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326856-B1 | PYRIDINE DERIVATIVES WITH IKB-KINASE (IKK-BETA) INHIBITING ACTIVITY | BAYER HEALTHCARE AG (DE) | 2007-12-19 | — | — | EP | disclosed |