Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 4/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13949861 | 0.91 | HDAC1 (0.69) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL8241774 | 0.87 | HDAC1 (0.72) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL14340023 | 0.84 | HDAC1 (0.61) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL13949896 | 0.81 | HDAC1 (0.65) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL14340266 | 0.80 | HDAC1 (0.72) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL15482180 | 0.80 | HDAC1 (0.77) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL23054920 | 0.79 | HDAC1 (0.46) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL14394459 | 0.79 | HDAC1 (0.53) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL14340000 | 0.79 | HDAC1 (0.70) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL13949863 | 0.77 | HDAC1 (0.71) | HDAC1HDAC3HDAC4HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1870399-A1 | HYDROXAMATE DERIVATIVES USEFUL AS DEACETYLASE INHIBITORS | Novartis AG (CH) | 2007-12-26 | — | — | EP | disclosed |