⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL85839 | 0.73 | — | — | |
| SCHEMBL16312548 | 0.73 | — | — | |
| SCHEMBL3347615 | 0.73 | — | — | |
| SCHEMBL2650130 | 0.73 | — | — | |
| SCHEMBL12696702 | 0.73 | — | — | |
| SCHEMBL636305 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL25302426 | 0.71 | — | — | |
| SCHEMBL19296416 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL2651912 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL2436911 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639577-B1 | Phosphonooxymethyl or methylthiomethyl ethers of taxane derivatives as antitumor agents | BRISTOL MYERS SQUIBB CO (US) | 2002-05-15 | — | — | EP | claimed |
| US-20010023255-A1 | PHOSPHONOOXYMETHYL ETHERS OF TAXANE DERIVATIVES | GOLIK JERZY (US) | 2001-09-20 | — | — | US | claimed |
| EP-0604910-B1 | Phosphonooxymethyl ethers of taxane derivatives | BRISTOL MYERS SQUIBB CO (US) | 2000-06-14 | — | — | EP | claimed |
| CN-1237580-A | Phosphononooxymethyl ethers of taxame derivatives | BRISTOL MYERS SQUIBB CO (US) | 1999-12-08 | — | — | CN | claimed |
| EP-0639577-A1 | Phosphonooxymethyl or methylthiomethyl ethers of taxane derivatives as antitumor agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-02-22 | — | — | EP | claimed |
| EP-0604910-A1 | Phosphonooxymethyl ethers of taxane derivatives | Bristol-Myers Squibb Company (US) | 1994-07-06 | — | — | EP | claimed |
| JP-7002885-A | — | — | None | — | — | JP | disclosed |
| JP-7149779-A | — | — | None | — | — | JP | disclosed |
| US-8558019-B2 | Thiolated paclitaxels for reaction with gold nanoparticles as drug delivery agents | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2013-10-15 | — | — | US | disclosed |
| US-20110144163-A1 | THIOLATED PACLITAXELS FOR REACTION WITH GOLD NANOPARTICLES AS DRUG DELIVERY AGENTS | ZAHAV BIOSCIENCES LLC | 2011-06-16 | — | — | US | disclosed |
| EP-1877403-B1 | MONO-LYSINE SALTS OF AZOLE COMPOUNDS | EISAI R&D MAN CO LTD (JP) | 2011-03-30 | — | — | EP | disclosed |
| EP-2217063-A1 | THIOLATED PACLITAXELS FOR REACTION WITH GOLD NANOPARTICLES AS DRUG DELIVERY AGENTS | Virginia Tech Intellectual Properties, Inc. (US) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009062138-A1 | THIOLATED PACLITAXELS FOR REACTION WITH GOLD NANOPARTICLES AS DRUG DELIVERY AGENTS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2009-05-14 | — | — | WO | disclosed |
| CN-1237580-A | Phosphononooxymethyl ethers of taxame derivatives | BRISTOL MYERS SQUIBB CO (US) | 1999-12-08 | — | — | CN | disclosed |
| CN-1174838-A | Taxusane phosphonic oxygen methyl ether derivant | BRISTOL MYERS SQUIBB CO (US) | 1998-03-04 | — | — | CN | disclosed |
| US-5646176-A | Phosphonooxymethyl ethers of taxane derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-07-08 | — | — | US | disclosed |
| JP-H07149779-A | PHOSPHONOOXYMETHYL ETHER DERIVATIVE OF TAXANE | BRISTOL MYERS SQUIBB CO | 1995-06-13 | — | — | JP | disclosed |
| EP-0639577-A1 | Phosphonooxymethyl or methylthiomethyl ethers of taxane derivatives as antitumor agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-02-22 | — | — | EP | disclosed |
| JP-H072885-A | PHOSPHONOOXYMETHYL ETHER OF TAXANE DERIVATIVE | BRISTOL MYERS SQUIBB CO | 1995-01-06 | — | — | JP | disclosed |
| EP-0604910-A1 | Phosphonooxymethyl ethers of taxane derivatives | Bristol-Myers Squibb Company (US) | 1994-07-06 | — | — | EP | disclosed |