SCHEMBL1434271

SCHEMBL1434271

C=CC(=O)OCCC(O)CCl

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.50
ALDH1A1 P00352 4/20 0.50
TP53 P04637 3/20 0.50
HIF1A Q16665 3/20 0.50
CYP3A4 P08684 2/20 0.50
HSD17B10 Q99714 1/20 0.50
HPGD P15428 1/20 0.46
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
THRB P10828 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6368712 0.88 TSHR (0.58) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL19456772 0.82 TSHR (0.57) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28744778 0.82 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29277897 0.82 TSHR (0.57) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3292973 0.82 TSHR (0.57) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8965488 0.82 TSHR (0.53) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1014076 0.81 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28972110 0.81 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9838899 0.81 TSHR (0.61) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27522591 0.80 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104262645-A Method for preparing granularity controllable narrow range polymer micro-nano spheres CHINESE ACAD INST CHEMISTRY 2015-01-07 CN claimed
CN-1370170-A DNA methyltransferase inhibitors PENN STATE RES FOUND (US) 2002-09-18 CN claimed
CN-104262645-A Method for preparing granularity controllable narrow range polymer micro-nano spheres CHINESE ACAD INST CHEMISTRY 2015-01-07 CN disclosed
CN-101578320-B Novel polyimide precursor composition, use thereof and process for producing the same KANEGAFUCHI CHEMICAL IND 2011-10-05 CN disclosed
CN-102149732-A Catalyst for living radical polymerization UNIV KYOTO 2011-08-10 CN disclosed
EP-1819737-B1 PHOTOCURABLE MICHAEL ADDITION POLYMERS 3M INNOVATIVE PROPERTIES CO (US) 2011-03-30 EP disclosed
CN-100558754-C The soil release agent and the manufacture method thereof that contain fluorinated copolymer DAIKIN IND LTD (JP) 2009-11-11 CN disclosed
CN-101578320-A Novel polyimide precursor composition, use thereof and process for producing the same KANEKA CORP (JP) 2009-11-11 CN disclosed
CN-101517018-A Oil-proof paper DOW CORNING (US) 2009-08-26 CN disclosed
CN-101479200-A Entrapping immobilization pellets, wastewater treatment system and wastewater treatment method using the same HITACHI PLANT TECHNOLOGYIES LT (JP) 2009-07-08 CN disclosed
CN-100376649-C Anisotropic conductive film BRIDGESTONE CORP (JP) 2008-03-26 CN disclosed
CN-1973000-A Resin composition and molded product thereof DAIKIN IND LTD (JP) 2007-05-30 CN disclosed
CN-1972966-A Soil release agent containing fluorine-containing copolymer and method for producing same DAIKIN IND LTD (JP) 2007-05-30 CN disclosed
CN-1277846-C Organic-inorganic nanocomposite and preparation method thereof LG CHEMICAL LTD (KR) 2006-10-04 CN disclosed
WO-2006065369-A2 PHOTOCURABLE MICHAEL ADDITION POLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-06-22 WO disclosed
US-20060128825-A1 Photocurable michael addition polymers 3M INNOVATIVE PROPERTIES COMPANY 2006-06-15 US disclosed
CN-1639294-A Anisotropic conductive film BRIDGESTONE CORP (JP) 2005-07-13 CN disclosed
CN-1159362-C Blocked polyisocyanates and their use ������������ʽ���� 2004-07-28 CN disclosed
CN-1498228-A Organic-inorganic nanocomposite and preparation method thereof LG��ѧ��ʽ���� 2004-05-19 CN disclosed
CN-1205717-A Novel blocked polyisocyanate and uses thereof ASAHI K K K K (JP) 1999-01-20 CN disclosed