Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.67 |
| ▸ | PPARA | Q07869 | 16/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4940710 | 0.81 | PPARG (0.46) | PPARGPPARA | |
| SCHEMBL4940715 | 0.81 | PPARG (0.46) | PPARGPPARA | |
| SCHEMBL12812177 | 0.81 | PPARG (0.77) | PPARGPPARAPTPN1 | |
| SCHEMBL13418276 | 0.81 | PPARG (0.77) | PPARGPPARAPTPN1 | |
| SCHEMBL1341176 | 0.79 | PPARG (0.41) | PPARGPPARA | |
| SCHEMBL1435567 | 0.79 | PPARG (0.57) | PPARGPPARAPTPN1 | |
| SCHEMBL11516826 | 0.79 | PPARG (0.79) | PPARGPPARA | |
| SCHEMBL5599872 | 0.78 | PPARG (0.47) | PPARGPPARA | |
| SCHEMBL4868233 | 0.78 | PPARG (0.47) | PPARGPPARA | |
| SCHEMBL13418302 | 0.77 | PPARA (0.81) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742927-B1 | BUTANOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND THERAPEUTIC APPLICATIONS THREREOF | MERCK PATENT GMBH (DE) | 2011-03-30 | — | — | EP | claimed |
| US-7678831-B2 | Butanoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and therapeutic applications thereof | MERCK PATENT GMBH (DE) | 2010-03-16 | — | — | US | claimed |
| US-20080032982-A1 | Butanoic Acid Derivatives, Processes For The Preparation Thereof, Pharmaceutical Compositions Comprising Them, And Therapeutic Applications Thereof | MERCK PATENT GMBH (DE) | 2008-02-07 | — | — | US | claimed |
| EP-1742927-A1 | BUTANOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND THERAPEUTIC APPLICATIONS THREREOF | MERCK PATENT GmbH (DE) | 2007-01-17 | — | — | EP | claimed |
| WO-2005105764-A1 | BUTANOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND THERAPEUTIC APPLICATIONS THREREOF | MERCK PATENT GMBH (DE) | 2005-11-10 | — | — | WO | claimed |
| EP-1742927-B1 | BUTANOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND THERAPEUTIC APPLICATIONS THREREOF | MERCK PATENT GMBH (DE) | 2011-03-30 | — | — | EP | disclosed |
| EP-1742927-B1 | BUTANOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND THERAPEUTIC APPLICATIONS THREREOF | MERCK PATENT GMBH (DE) | 2011-03-30 | — | — | EP | disclosed |
| US-7678831-B2 | Butanoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and therapeutic applications thereof | MERCK PATENT GMBH (DE) | 2010-03-16 | — | — | US | disclosed |
| US-7678831-B2 | Butanoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and therapeutic applications thereof | MERCK PATENT GMBH (DE) | 2010-03-16 | — | — | US | disclosed |
| US-7678831-B2 | Butanoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and therapeutic applications thereof | MERCK PATENT GMBH (DE) | 2010-03-16 | — | — | US | disclosed |
| US-20080032982-A1 | Butanoic Acid Derivatives, Processes For The Preparation Thereof, Pharmaceutical Compositions Comprising Them, And Therapeutic Applications Thereof | MERCK PATENT GMBH (DE) | 2008-02-07 | — | — | US | disclosed |
| US-20080032982-A1 | Butanoic Acid Derivatives, Processes For The Preparation Thereof, Pharmaceutical Compositions Comprising Them, And Therapeutic Applications Thereof | MERCK PATENT GMBH (DE) | 2008-02-07 | — | — | US | disclosed |
| US-20080032982-A1 | Butanoic Acid Derivatives, Processes For The Preparation Thereof, Pharmaceutical Compositions Comprising Them, And Therapeutic Applications Thereof | MERCK PATENT GMBH (DE) | 2008-02-07 | — | — | US | disclosed |
| EP-1742927-A1 | BUTANOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND THERAPEUTIC APPLICATIONS THREREOF | MERCK PATENT GmbH (DE) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005105764-A1 | BUTANOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND THERAPEUTIC APPLICATIONS THREREOF | MERCK PATENT GMBH (DE) | 2005-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080032982-A1 | Butanoic Acid Derivatives, Processes For The Preparation Thereof, Pharmaceutical Compositions Comprising Them, And Therapeutic Applications Thereof | PPARA, PPARD, PPARG | PPARG 3/4885PPARA 1/4885PTPN1 3086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.