Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.67 |
| ▸ | F10 | P00742 | 17/20 | 0.51 |
| ▸ | F2 | P00734 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5534823 | 0.99 | KCNH2 (0.68) | KCNH2F10F2 | |
| SCHEMBL14345195 | 0.98 | KCNH2 (0.68) | KCNH2F10F2 | |
| SCHEMBL5533987 | 0.92 | F10 (0.58) | KCNH2F10F2 | |
| SCHEMBL14345251 | 0.92 | KCNH2 (0.72) | KCNH2F10F2 | |
| SCHEMBL5532187 | 0.91 | KCNH2 (0.67) | KCNH2F10F2 | |
| SCHEMBL10178615 | 0.91 | KCNH2 (0.77) | KCNH2F10F2 | |
| SCHEMBL5533469 | 0.91 | F10 (0.59) | KCNH2F10F2 | |
| SCHEMBL14345193 | 0.91 | KCNH2 (0.71) | KCNH2F10F2 | |
| SCHEMBL10181675 | 0.90 | KCNH2 (0.78) | KCNH2F10F2 | |
| SCHEMBL14345327 | 0.89 | KCNH2 (0.68) | KCNH2F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |