Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345294 | 0.92 | F10 (0.81) | F10KCNH2 | |
| SCHEMBL5531959 | 0.91 | F10 (0.57) | F10KCNH2F2PLGF7 | |
| SCHEMBL14345336 | 0.91 | F10 (0.63) | F10KCNH2F2 | |
| SCHEMBL14345324 | 0.90 | F10 (0.55) | F10KCNH2F2PLGF7 | |
| SCHEMBL14345447 | 0.89 | F10 (0.84) | F10KCNH2F2 | |
| SCHEMBL14345381 | 0.88 | F10 (0.54) | F10KCNH2F2PLGF7 | |
| SCHEMBL14345380 | 0.88 | F10 (0.54) | F10KCNH2F2PLGF7 | |
| SCHEMBL14345260 | 0.87 | F10 (0.52) | F10F2PLGF7F3 | |
| SCHEMBL5535526 | 0.84 | F10 (0.68) | F10KCNH2F2 | |
| SCHEMBL14345248 | 0.83 | F10 (0.50) | F10KCNH2F2PLGF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |