Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10178609 | 0.89 | F10 (0.59) | F10MEN1KMT2APOLBRAB9A | |
| SCHEMBL5530751 | 0.89 | F10 (0.45) | F10MEN1KMT2ARAB9A | |
| SCHEMBL5532074 | 0.88 | F10 (0.60) | F10 | |
| SCHEMBL12132860 | 0.88 | F10 (0.73) | F10RAB9A | |
| SCHEMBL14629912 | 0.86 | F10 (0.56) | F10MEN1KMT2A | |
| SCHEMBL5534838 | 0.85 | F10 (0.76) | F10 | |
| SCHEMBL5530287 | 0.84 | F10 (0.64) | F10RAB9A | |
| SCHEMBL14345361 | 0.82 | F10 (0.65) | F10DEGS1 | |
| SCHEMBL14366123 | 0.82 | F10 (0.54) | F10MEN1KMT2APOLBRAB9A | |
| SCHEMBL14345240 | 0.81 | F10 (0.53) | F10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |