Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345112 | 0.91 | F10 (0.61) | F10KCNH2ALOX5 | |
| SCHEMBL5533865 | 0.91 | F10 (0.57) | F10KCNH2 | |
| SCHEMBL5535269 | 0.90 | F10 (0.53) | F10KCNH2 | |
| SCHEMBL14345296 | 0.87 | KCNH2 (0.61) | F10KCNH2ITGB3ITGA2B | |
| SCHEMBL14345163 | 0.86 | F10 (0.58) | F10KCNH2 | |
| SCHEMBL14345431 | 0.85 | KCNH2 (0.59) | F10KCNH2ALOX5ITGB3ITGA2B | |
| SCHEMBL5528854 | 0.84 | F10 (0.48) | F10KCNH2ITGB3ITGA2B | |
| SCHEMBL10178319 | 0.83 | F10 (0.56) | F10KCNH2 | |
| SCHEMBL14345441 | 0.83 | F10 (0.44) | F10KCNH2ITGB3ITGA2B | |
| SCHEMBL14345258 | 0.82 | F10 (0.48) | F10KCNH2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |