SCHEMBL14346166

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14346156	0.92	CDK2 (0.66)	CDK2CDK9CCNE1CDK5CDK1
	SCHEMBL14364529	0.91	CDK2 (0.78)	CDK2CDK9CCNE1CDK5CDK1
	SCHEMBL14346562	0.91	CDK2 (0.78)	CDK2CDK9CCNE1CDK5CDK1
	SCHEMBL14346188	0.91	CDK2 (0.65)	CDK2CDK9CCNE1CDK5CDK1
	SCHEMBL14364531	0.90	CDK2 (0.76)	CDK2CDK9CCNE1CDK5CDK1
	SCHEMBL14364530	0.90	CDK2 (0.76)	CDK2CDK9CCNE1CDK5CDK1
	SCHEMBL16366036	0.90	CDK2 (0.84)	CDK2CDK9CCNE1CDK5CDK1
	SCHEMBL18738298	0.89	CDK2 (0.82)	CDK2CDK9CCNE1CDK5CDK1
	Dinaciclib SCHEMBL23682977	0.88	CDK2 (1.00)	CDK2CDK9CCNE1CDK5CDK1
	Dinaciclib SCHEMBL30176832	0.88	CDK2 (1.00)	CDK2CDK9CCNE1CDK5CDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.