Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 10/20 | 0.64 |
| ▸ | MAOB | P27338 | 6/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4340422 | 0.99 | F2R (0.63) | F2RMAOBMAOABCHEACHE | |
| SCHEMBL14346327 | 0.92 | F2R (0.64) | F2RMAOBMAOABCHEACHE | |
| Bromide SCHEMBL4353452 | 0.91 | F2R (0.63) | F2RMAOBMAOABCHEACHE | |
| SCHEMBL14346288 | 0.86 | F2R (0.69) | F2RMAOBMAOABCHEACHE | |
| SCHEMBL14369199 | 0.86 | F2R (0.53) | F2RMAOBMAOABCHEACHE | |
| Bromide SCHEMBL4347253 | 0.85 | F2R (0.67) | F2RMAOBMAOABCHEACHE | |
| SCHEMBL6360881 | 0.83 | F2R (0.65) | F2RMAOBMAOABCHEACHE | |
| Bromide SCHEMBL4340619 | 0.82 | F2R (0.64) | F2RMAOBMAOABCHEACHE | |
| SCHEMBL14369137 | 0.82 | F2R (0.53) | F2RMAOBMAOABCHEACHE | |
| SCHEMBL14346350 | 0.82 | F2R (0.63) | F2RMAOBMAOABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304083-B2 | 2-iminoimidazole derivatives (2) | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-12-04 | — | — | US | disclosed |