Sugi Predict

Sugi Predict / Compounds / SCHEMBL14346352

SCHEMBL14346352

SCHEMBL14346352

C/N=c1/n(CC(=O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc(C(=O)N(C)C)n1Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ F2R P25116 10/20 0.53
▸ MAOB P27338 7/20 0.42
▸ MAOA P21397 4/20 0.42
▸ ACHE P22303 3/20 0.42
▸ BCHE P06276 2/20 0.42
▸ BRD4 O60885 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL4353524 0.99 F2R (0.52) F2RMAOBMAOAACHEBCHE
Bromide SCHEMBL4353527 0.99 F2R (0.52) F2RMAOBMAOAACHEBCHE
SCHEMBL14369207 0.92 F2R (0.52) F2RMAOBMAOAACHEBCHE
SCHEMBL14346350 0.87 F2R (0.63) F2RMAOBMAOAACHEBCHE
Bromide SCHEMBL4340412 0.86 F2R (0.62) F2RMAOBMAOAACHEBCHE
SCHEMBL14346347 0.84 F2R (0.56) F2RMAOBMAOAACHEBCHE
Bromide SCHEMBL4351068 0.83 F2R (0.55) F2RMAOBMAOAACHEBCHE
Bromide SCHEMBL4351069 0.83 F2R (0.55) F2RMAOBMAOAACHEBCHE
SCHEMBL14369044 0.80 F2R (0.58) F2RMAOBMAOAACHEBCHE
SCHEMBL14368585 0.79 F2R (0.56) F2RMAOBMAOAACHEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7304083-B2 2-iminoimidazole derivatives (2) EISAI R&D MANAGEMENT CO., LTD. (JP) 2007-12-04 — — US disclosed
US-7304083-B2 2-iminoimidazole derivatives (2) EISAI R&D MANAGEMENT CO., LTD. (JP) 2007-12-04 — — US disclosed