Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.78 |
| ▸ | F2 | P00734 | 4/20 | 0.62 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 2/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354752 | 0.90 | F10 (0.81) | F10F2SLC29A1 | |
| SCHEMBL5643012 | 0.88 | F10 (1.00) | F10F2SLC29A1 | |
| SCHEMBL5872456 | 0.88 | F10 (0.59) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL16948138 | 0.86 | F10 (0.64) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL5307046 | 0.86 | F10 (0.67) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL2000886 | 0.86 | F10 (0.63) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL15731769 | 0.86 | F10 (0.67) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL1995178 | 0.85 | F10 (0.62) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL18660272 | 0.85 | F10 (0.62) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL18040316 | 0.84 | F10 (0.61) | F10F2SLC29A1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312214-B2 | 1, 1-disubstituted cycloalkyl derivatives as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-25 | — | — | US | disclosed |