SCHEMBL143541

SCHEMBL143541

O=C(O)c1cc(SSc2ccc([N+](=O)[O-])c(C(=O)O)c2)ccc1[N+](=O)[O-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DTYMK P23919 1/20 1.00
CASP6 P55212 1/20 0.49
TSHR P16473 3/20 0.45
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
POLB P06746 2/20 0.44
HSP90AA1 P07900 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
TTR P02766 1/20 0.41
PPOX P50336 1/20 0.41
BCL2L1 Q07817 1/20 0.41
ALDH1A1 P00352 2/20 0.41
LMNA P02545 2/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
HTT P42858 1/20 0.40
GSTP1 P09211 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26775 1.00 DTYMK (1.00) DTYMKCASP6TSHRMEN1KMT2A
SCHEMBL29353295 1.00 DTYMK (1.00) DTYMKCASP6TSHRMEN1KMT2A
SCHEMBL29388000 0.98 DTYMK (0.97) DTYMKCASP6TSHRMEN1KMT2A
SCHEMBL8577281 0.98 DTYMK (0.97) DTYMKCASP6TSHRMEN1KMT2A
SCHEMBL19885315 0.92 DTYMK (0.85) DTYMKCASP6TSHRMEN1KMT2A
SCHEMBL12269946 0.92 DTYMK (0.85) DTYMKCASP6MEN1KMT2APOLB
SCHEMBL16489112 0.91 DTYMK (0.82) DTYMKCASP6TSHRMEN1KMT2A
SCHEMBL10883375 0.91 DTYMK (0.82) DTYMKCASP6TSHRMEN1KMT2A
SCHEMBL13715527 0.90 DTYMK (0.82) DTYMKCASP6TSHRMEN1KMT2A
SCHEMBL7522507 0.89 DTYMK (0.80) DTYMKCASP6TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4376 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146955-A1 SERS BIOSENSOR BASED ON CRISPR/CAS13A SYSTEM AND APPLICATION THEREOF NANJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS (CN) 2026-05-28 US claimed
CN-122057046-A Paclitaxel inclusion compound and preparation method and application thereof 江南大学 2026-05-19 CN claimed
US-12618779-B2 Fluorescent ellman assay for free thiol detection GENENTECH, INC. (US) 2026-05-05 US claimed
EP-4724110-A1 PROCESS FOR PREPARING ANTIBODY-DRUG CONJUGATES WITH IMPROVED HOMOGENEITY WUXI XDC SINGAPORE PRIVATE LIMITED (SG) 2026-04-15 EP claimed
EP-4705321-A2 SPYCATCHER ANALOGS AND USES THEREOF Bio-Rad ABD Serotec GmbH (DE) 2026-03-11 EP claimed
CN-121575086-A One-dimensional Au/WOXBase SERS label and preparation method and application thereof 中国人民解放军军事科学院军事医学研究院 2026-02-27 CN claimed
EP-4694868-A1 PROTEIN PARTICLES AND METHODS OF MAKING AND USING THE SAME Dairy Management Inc. (US) 2026-02-18 EP claimed
US-20250356947-A1 GENOME WIDE TUMOR DERIVED GENE EXPRESSION BASED SIGNATURES ASSOCIATED WITH POOR PROGNOSIS FOR MELANOMA PATIENTS WITH EARLY STAGE DISEASE MERCK SHARP & DOHME LLC (US) 2025-11-20 US claimed
US-12466874-B2 Prevention of protein disulfide bond reduction MEDIMMUNE LLC (US) 2025-11-11 US claimed
US-20250314659-A1 IN-SITU MEMBRANE PROTEIN DIMERIZATION STATE DETECTION KIT AND USE THEREOF NANJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS (CN) 2025-10-09 US claimed
US-20100143322-A1 USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE PLT PATENT & LICENCE TRADING LTD., C/O THE B-NET (GB) 2010-06-10 US claimed
JP-3672307-B2 2005-07-20 JP claimed
EP-0630402-B1 NEW KETONIC ESTER REDUCTASES, ITS PREPARATION AND USE FOR ENZYMATIC REDOX REACTIONS FORSCHUNGSZENTRUM JUELICH GMBH (DE) 1997-06-04 EP claimed
EP-0630402-A1 NEW KETONIC ESTER REDUCTASES, ITS PREPARATION AND USE FOR ENZYMATIC REDOX REACTIONS. FORSCHUNGSZENTRUM JUELICH GMBH (DE) 1994-12-28 EP claimed
EP-0233044-B1 Process for purifying recombinant proteins, and use of products thereof CAMBRIDGE BIOTECH CORP (US) 1994-08-03 EP claimed
WO-1993018138-A1 NEW KETONIC ESTER REDUCTASES, ITS PREPARATION AND USE FOR ENZYMATIC REDOX REACTIONS Forschungszentrum Jülich GmbH (DE) 1993-09-16 WO claimed
US-4734362-A Process for purifying recombinant proteins, and products thereof CAMBRIDGE BIOSCIENCE CORPORATION (US) 1988-03-29 US claimed
EP-0233044-A2 Process for purifying recombinant proteins, and use of products thereof CAMBRIDGE BIOTECH CORPORATION (US) 1987-08-19 EP claimed
WO-1987004726-A1 PROCESS FOR PURIFYING RECOMBINANT PROTEINS, AND PRODUCTS THEREOF CAMBRIDGE BIOSCIENCE CORPORATION (US) 1987-08-13 WO claimed
US-4330621-A Assay for aminoglycosides WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1982-05-18 US claimed