SCHEMBL14355014

SCHEMBL14355014

CCOCCC(COc1ccc(C(F)(F)F)cc1)CSc1ccc(OCCOO)c(C)c1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.68
PPARA Q07869 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14355010 0.93 PPARD (0.75) PPARDPPARA
SCHEMBL7018932 0.92 PPARD (0.68) PPARDPPARA
SCHEMBL14354998 0.92 PPARD (0.64) PPARDPPARA
SCHEMBL14355013 0.91 PPARD (0.63) PPARDPPARA
SCHEMBL14355012 0.91 PPARD (0.73) PPARDPPARA
SCHEMBL14354996 0.90 PPARD (0.74) PPARDPPARA
SCHEMBL14354994 0.90 PPARD (0.74) PPARDPPARA
SCHEMBL14354999 0.89 PPARD (0.61) PPARDPPARA
SCHEMBL7015478 0.89 PPARD (0.67) PPARDPPARA
SCHEMBL14355001 0.88 PPARD (0.60) PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7301050-B2 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs JANSSEN PHARMACEUTICAL N.V. (BE) 2007-11-27 US disclosed