⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1752303 | 0.86 | — | — | |
| SCHEMBL4528423 | 0.86 | — | — | |
| SCHEMBL14355172 | 0.85 | — | — | |
| SCHEMBL20471114 | 0.84 | — | — | |
| SCHEMBL20194039 | 0.84 | — | — | |
| SCHEMBL26212138 | 0.73 | — | — | |
| SCHEMBL21137508 | 0.73 | — | — | |
| SCHEMBL15836320 | 0.72 | — | — | |
| SCHEMBL22203037 | 0.71 | — | — | |
| SCHEMBL19219849 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301019-B2 | Method for the preparation of maytansinoid esters | IMMUNOGEN, INC. (US) | 2007-11-27 | — | — | US | disclosed |
| US-7301019-B2 | Method for the preparation of maytansinoid esters | IMMUNOGEN, INC. (US) | 2007-11-27 | — | — | US | disclosed |