Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14387449 | 0.81 | POLB (0.41) | TP53POLB | |
| SCHEMBL25443684 | 0.78 | PIK3CD (0.50) | PIK3CDTP53POLB | |
| SCHEMBL6729529 | 0.75 | PIK3CD (0.52) | PIK3CDTP53POLB | |
| SCHEMBL13218356 | 0.71 | PIK3CD (0.48) | PIK3CDPOLB | |
| SCHEMBL3162091 | 0.71 | DPP4 (0.44) | PIK3CD | |
| SCHEMBL13328504 | 0.71 | PIK3CD (0.48) | PIK3CD | |
| SCHEMBL27510202 | 0.71 | DPP4 (0.44) | PIK3CD | |
| SCHEMBL6729525 | 0.70 | PIK3CD (0.52) | PIK3CDPOLB | |
| SCHEMBL8435450 | 0.70 | PIK3CD (0.52) | PIK3CDPOLB | |
| SCHEMBL8435445 | 0.69 | PIK3CD (0.50) | PIK3CDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300948-B2 | Alkynyl compounds as non nucleoside reverse transcriptase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-11-27 | — | — | US | disclosed |