Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 19/20 | 0.72 |
| ▸ | MC5R | P33032 | 1/20 | 0.49 |
| ▸ | MC3R | P41968 | 1/20 | 0.49 |
| ▸ | MC1R | Q01726 | 1/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4515127 | 1.00 | MC4R (0.72) | MC4RMC5RMC3RMC1RSMYD3 | |
| SCHEMBL14591449 | 0.90 | MC4R (0.70) | MC4RMC5RMC3RMC1RSMYD3 | |
| SCHEMBL14355922 | 0.90 | MC4R (0.75) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14356065 | 0.89 | MC4R (0.72) | MC4RMC5RMC3RMC1RSMYD3 | |
| SCHEMBL4528940 | 0.88 | MC4R (0.69) | MC4RMC5RMC3RMC1R | |
| SCHEMBL4515558 | 0.88 | MC4R (0.66) | MC4RMC5RMC3RMC1R | |
| SCHEMBL4517165 | 0.88 | MC4R (0.70) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14356091 | 0.87 | MC4R (0.72) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14356090 | 0.87 | MC4R (0.72) | MC4RMC5RMC3RMC1R | |
| SCHEMBL4512099 | 0.87 | MC4R (0.65) | MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |