Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 19/20 | 0.86 |
| ▸ | MC5R | P33032 | 2/20 | 0.48 |
| ▸ | MC3R | P41968 | 2/20 | 0.48 |
| ▸ | MC1R | Q01726 | 2/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4514833 | 1.00 | MC4R (0.86) | MC4RMC5RMC3RMC1RSMYD3 | |
| SCHEMBL14640081 | 0.89 | MC4R (0.75) | MC4RMC5RMC3RMC1R | |
| SCHEMBL30661855 | 0.89 | MC4R (0.78) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14355922 | 0.89 | MC4R (0.75) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13790258 | 0.88 | MC4R (0.74) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14640075 | 0.88 | MC4R (0.76) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14640079 | 0.88 | MC4R (0.73) | MC4RMC5RMC3RMC1R | |
| SCHEMBL30661852 | 0.88 | MC4R (0.73) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14356090 | 0.86 | MC4R (0.72) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14356091 | 0.86 | MC4R (0.72) | MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |