Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.46 |
| ▸ | RAB9A | P51151 | 9/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9290152 | 0.88 | NPC1 (0.48) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL14164148 | 0.84 | NPC1 (0.51) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL14356289 | 0.82 | NPC1 (0.61) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL17971498 | 0.79 | NPC1 (0.65) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL17971504 | 0.79 | NPC1 (0.65) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL21742767 | 0.76 | CYP2A6 (0.54) | CYP19A1CYP2E1CYP3A4CYP2D6CYP2A6 | |
| SCHEMBL20358566 | 0.74 | NPC1 (0.59) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL17971500 | 0.74 | NPC1 (0.64) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL17971507 | 0.74 | NPC1 (0.64) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL20357007 | 0.74 | NPC1 (0.51) | NPC1RAB9ANTSR1HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300770-B2 | Detection of microbe contamination on elastomeric articles | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2007-11-27 | — | — | US | disclosed |