Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.68 |
| ▸ | FYN | P06241 | 6/20 | 0.53 |
| ▸ | PTK2 | Q05397 | 7/20 | 0.50 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4595806 | 0.95 | PIK3CG (0.76) | PIK3CGFYNPTK2CAMK2DBRAF | |
| SCHEMBL14357025 | 0.88 | PIK3CG (0.87) | PIK3CGFYNBRAFTGFBR2RET | |
| SCHEMBL14301973 | 0.87 | PIK3CG (0.69) | PIK3CGFYNPTK2CAMK2DBRAF | |
| SCHEMBL4335832 | 0.86 | PIK3CG (0.72) | PIK3CGFYNPTK2CAMK2DRET | |
| SCHEMBL14357032 | 0.84 | PIK3CG (0.66) | PIK3CGFYNTGFBR2 | |
| SCHEMBL14302662 | 0.84 | PIK3CG (0.66) | PIK3CGFYNBRAFTGFBR2RET | |
| SCHEMBL14308687 | 0.83 | PIK3CG (0.65) | PIK3CGFYNBRAFTGFBR2RET | |
| SCHEMBL4328626 | 0.83 | FYN (0.77) | PIK3CGFYNPTK2CAMK2DTGFBR2 | |
| SCHEMBL4556978 | 0.82 | PIK3CG (0.85) | PIK3CGFYNPTK2BRAFTGFBR2 | |
| SCHEMBL4594791 | 0.81 | PIK3CG (1.00) | PIK3CGFYNPTK2BRAFTGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147647-A1 | PYRAZOLOPYRIMIDINES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME. | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-12-27 | — | — | WO | disclosed |