Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 7/20 | 0.82 |
| ▸ | TGFBR2 | P37173 | 4/20 | 0.56 |
| ▸ | ACVR2A | P27037 | 3/20 | 0.56 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.52 |
| ▸ | PIM1 | P11309 | 5/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4333198 | 0.90 | FYN (1.00) | FYNTGFBR2ACVR2ATGFBR1PIK3CG | |
| SCHEMBL4344839 | 0.89 | FYN (0.80) | FYNTGFBR2ACVR2ATGFBR1PIK3CG | |
| SCHEMBL4338950 | 0.89 | FYN (1.00) | FYNTGFBR2ACVR2ATGFBR1PIK3CG | |
| SCHEMBL30521945 | 0.89 | FYN (1.00) | FYNTGFBR2ACVR2ATGFBR1PIK3CG | |
| SCHEMBL4344765 | 0.89 | FYN (0.79) | FYNTGFBR2ACVR2ATGFBR1PIK3CG | |
| SCHEMBL4595945 | 0.87 | FYN (0.78) | FYNTGFBR2ACVR2ATGFBR1PIK3CG | |
| SCHEMBL4347235 | 0.87 | FYN (0.74) | FYNTGFBR2ACVR2ATGFBR1PIK3CG | |
| SCHEMBL4595121 | 0.86 | FYN (0.77) | FYNTGFBR2ACVR2ATGFBR1PIK3CG | |
| SCHEMBL4333107 | 0.86 | FYN (0.79) | FYNTGFBR2ACVR2ATGFBR1PIK3CG | |
| SCHEMBL4332798 | 0.86 | FYN (1.00) | FYNTGFBR2ACVR2ATGFBR1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147647-A1 | PYRAZOLOPYRIMIDINES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME. | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-12-27 | — | — | WO | disclosed |