Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 18/20 | 0.68 |
| ▸ | PIM2 | Q9P1W9 | 12/20 | 0.64 |
| ▸ | FLT3 | P36888 | 4/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.61 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4328408 | 0.85 | PIK3CG (0.72) | PIM1PIM2FLT3PIK3CGRET | |
| SCHEMBL4692526 | 0.82 | PIM1 (0.73) | PIM1PIM2FLT3PIK3CGRET | |
| SCHEMBL4595073 | 0.81 | PIM1 (1.00) | PIM1PIM2FLT3PIK3CG | |
| SCHEMBL4335504 | 0.81 | PIM1 (0.79) | PIM1PIM2FLT3PIK3CG | |
| SCHEMBL1424084 | 0.80 | PIK3CG (0.71) | PIM1PIM2FLT3PIK3CGRET | |
| SCHEMBL1424085 | 0.80 | PIK3CG (0.71) | PIM1PIM2FLT3PIK3CGRET | |
| SCHEMBL16216068 | 0.80 | PIM1 (0.78) | PIM1PIM2FLT3PIK3CG | |
| SCHEMBL4339100 | 0.79 | PIM1 (0.72) | PIM1PIM2FLT3PIK3CGRET | |
| SCHEMBL4332530 | 0.79 | PIM1 (0.72) | PIM1PIM2FLT3PIK3CGRET | |
| SCHEMBL4333807 | 0.79 | PIM1 (0.68) | PIM1PIM2FLT3PIK3CGRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147647-A1 | PYRAZOLOPYRIMIDINES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME. | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-12-27 | — | — | WO | disclosed |