Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5396775 | 1.00 | BDKRB1 (0.51) | BDKRB1 | |
| Hydrochloric Acid SCHEMBL5383429 | 0.99 | BDKRB1 (0.51) | BDKRB1 | |
| SCHEMBL5393965 | 0.93 | BDKRB1 (0.50) | BDKRB1 | |
| Hydrochloric Acid SCHEMBL5383437 | 0.92 | BDKRB1 (0.49) | BDKRB1 | |
| SCHEMBL5385083 | 0.90 | BDKRB1 (0.49) | BDKRB1 | |
| Hydrochloric Acid SCHEMBL5383391 | 0.90 | BDKRB1 (0.49) | BDKRB1 | |
| SCHEMBL5385820 | 0.84 | CCR1 (0.38) | BDKRB1 | |
| SCHEMBL5392234 | 0.82 | BDKRB1 (0.50) | BDKRB1 | |
| SCHEMBL5195850 | 0.80 | BDKRB1 (0.51) | BDKRB1 | |
| SCHEMBL5384892 | 0.79 | BDKRB1 (0.67) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291642-B2 | Bradykinin-B1 antagonists, process for their preparation and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-11-06 | — | — | US | disclosed |
| US-7291642-B2 | Bradykinin-B1 antagonists, process for their preparation and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-11-06 | — | — | US | disclosed |